A missense mutation of Ip3r1 in Dp2 mice leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles
Bing Chen, Chong-Yang Qi, Li Chen, Meng-Jun Dai, Ya-You Miao, Rui Chen, Wan-E Wei, Shun Yang, Hongling Wang, Xiao-Ge Duan, Min-Wei Gong, Wang Yi, Zhengfeng Xue
This study identifies an Ip3r1 mutation in mice causing mydriasis and UPR activation in iris muscles without other phenotypes.
EXPERIMENTAL ANIMALS · Aug 7, 2019Peer-reviewedGenetics