BioinformaticsPLoS Computational BiologyPeer-reviewed
Evolution of tunnels in alpha/beta-hydrolase fold proteins - what can we learn from studying epoxide hydrolases?
Maria Bzówka, Karolina Mitusińska, Agata Raczyńska…·Artur Góra
The paper studies tunnel evolution in soluble epoxide hydrolases, finding conserved tunnel-lining residues and variable residues that respond to evolutionary pressure, proposing methods for tunnel design and enzyme reengineering.
11 citations