Author

Agata Raczyńska

Silesian University of TechnologyORCID 0000-0002-1884-3669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

Aleksandra SamoliD· 2 shared Artur GóraiD· 2 shared Karolina MitusińskaiD· 2 shared Maria BzówkaiD· 2 shared Jack A. TuszyńskiiD· 1 shared Tomasz MagdziarziD· 1 shared Tomasz SkalskiiD· 1 shared Weronika BagrowskaiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Aleksandra SamolORCID

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2 papers

Recent·Most cited

Evolution of tunnels in alpha/beta-hydrolase fold proteins - what can we learn from studying epoxide hydrolases?

Maria Bzówka, Karolina Mitusińska, Agata Raczyńska, Tomasz Skalski, Aleksandra Samol, Weronika Bagrowska, Tomasz Magdziarz, Artur Góra

The paper studies tunnel evolution in soluble epoxide hydrolases, finding conserved tunnel-lining residues and variable residues that respond to evolutionary pressure, proposing methods for tunnel design and enzyme reengineering.

PLoS Computational Biology · May 17, 2022Peer-reviewedBioinformatics

Structural and Evolutionary Analysis Indicate that the SARS-CoV-2 Mpro is an Inconvenient Target for Small-Molecule Inhibitors Design

Maria Bzówka, Karolina Mitusińska, Agata Raczyńska, Aleksandra Samol, Jack A. Tuszyński, Artur Góra

The paper analyzes the structural and evolutionary features of SARS-CoV-2 Mpro, finding that its active site differences and flexibility make it a poor target for small-molecule inhibitors.

International Journal of Molecular Sciences · Apr 28, 2020Peer-reviewedMolecular Biology