Eric S. Loker

Immune targets for schistosomiasis control identified by a genome-wide association study of East African snail vectors

This study identifies two genomic regions associated with schistosome resistance in Biomphalaria sudanica snails using a genome-wide association study.

The genome and transcriptome of the snail Biomphalaria sudanica s.l.: Immune gene diversification and highly polymorphic genomic regions in an important African vector of Schistosoma mansoni

This paper presents the first genome and transcriptome assembly of Biomphalaria sudanica s.l., identifies immune-related genes and polymorphic regions, and highlights potential pathogen recognition mechanisms in an African Schistosoma mansoni vector.

Bulinus snails in the Lake Victoria Basin in Kenya: systematics and their role as hosts for schistosomes

This study identifies Bulinus species in Kenya's Lake Victoria Basin and determines their role as hosts for Schistosoma species, finding that some species transmit S. haematobium while others transmit S. bovis.

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors

This study examines the transcriptomic responses of Biomphalaria pfeifferi and Schistosoma mansoni to niclosamide exposure, revealing differential gene expression patterns in snails and sporocysts under various stress conditions.

The in vivo transcriptome of Schistosoma mansoni in two prominent vector species, Biomphalaria pfeifferi and B. glabrata

This study characterizes the in vivo transcriptome of Schistosoma mansoni in two Biomphalaria snail species, revealing gene expression patterns during intramolluscan development and host interactions.