Jacob Adam Tennessen

Genomic Signatures of Microgeographic Adaptation in Anopheles coluzzii Along an Anthropogenic Gradient in Gabon

This study identifies genomic signatures of local adaptation in Anopheles coluzzii across urban, rural, and sylvatic sites in Gabon, revealing distinct genetic responses to human-driven selection pressures and environmental heterogeneity.

Population genomics of Anopheles darlingi, the principal South American malaria vector mosquito

This study analyzes whole genomes of 1094 Anopheles darlingi mosquitoes from six South American countries, revealing geographic structure, genetic diversity, and selection signals on cytochrome P450 genes.

Immune targets for schistosomiasis control identified by a genome-wide association study of East African snail vectors

This study identifies two genomic regions associated with schistosome resistance in Biomphalaria sudanica snails using a genome-wide association study.

The genome and transcriptome of the snail Biomphalaria sudanica s.l.: Immune gene diversification and highly polymorphic genomic regions in an important African vector of Schistosoma mansoni

This paper presents the first genome and transcriptome assembly of Biomphalaria sudanica s.l., identifies immune-related genes and polymorphic regions, and highlights potential pathogen recognition mechanisms in an African Schistosoma mansoni vector.

Comparative chemical genomics in Babesia species identifies the alkaline phosphatase phoD as a novel determinant of resistance

This paper identifies PhoD as a novel resistance determinant in Babesia species using comparative chemogenomics and validates its role through reverse genetics and functional perturbation.

PTC2 region genotypes counteract Biomphalaria glabrata population differences between M-line and BS90 in resistance to infection by Schistosoma mansoni

The paper tests if the PTC2 region explains resistance differences between two Biomphalaria glabrata strains to Schistosoma mansoni, but finds the BS90 haplotype increases susceptibility instead.

Integration of whole genome sequencing and transcriptomics reveals a complex picture of insecticide resistance in the major malaria vector Anopheles coluzzii

This study integrates whole genome sequencing and transcriptomics to identify multiple factors contributing to insecticide resistance in Anopheles coluzzii.