Author

Cécile Pascal

ORCID 0000-0002-2917-6558Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessia Tagliavini· 2 shared Anna M. UptoniD· 2 shared Chiara RoversiiD· 2 shared Clara Aguilar-PéreziD· 2 shared David J. Hermann· 2 shared Debra Flood· 2 shared Denise FedericoiD· 2 shared Khisimuzi E. Mdluli· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Alessia Tagliavini

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 23, 2026

Next Generation TB Drug Combinations from the Pan-TB Consortium: Combination Efficacy and Contributions of Individual Agents, Evaluated in a BALB/c Mouse TB Model

Sylvie Sordello, Alain Le Coupanec, Zoï Vahlas…·Anna M. Upton

The paper evaluates next-generation TB drug combinations in a mouse model, showing some regimens cure 90% of mice in under 2 months with faster sterilizing efficacy than existing treatments.

DOI 10.64898/2026.06.18.733138

mouseexperimental assay

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MicrobiologybioRxivPreprintMay 7, 2026

Nonclinical pharmacokinetics and relative efficacy of the first 25 novel tuberculosis drug combinations from the PAN-TB consortium: Use of the BALB/c relapsing mouse model and combination pharmacokinetics within a modeling-based framework

Sylvie Sordello, Alessia Tagliavini, Xavier Boulenc…·Anna M. Upton

The paper evaluates 25 tuberculosis drug combinations in a mouse model, finding 15 combinations with T90 <5 months and three top combinations curing 90% of mice in <3 months.

1 citation

mousestatistical model

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