Nonspecific interactions can lead to liquid-liquid phase separation in coiled-coil proteins models
Dominique A. Ramirez, Anastasia Shrimpton, Michael R. Shirts, Loren E. Hough
The paper shows that nonspecific interactions in coiled-coil proteins can lead to liquid-liquid phase separation, and that linker segments can enhance this process without altering interaction specificity.
Biophysical Journal · Nov 21, 2025Peer-reviewedBiophysics