Author

Joshua L. Payne

F. Hoffmann-La Roche AGORCID 0000-0002-2978-8423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:deep learning· 1

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Carlo De DonnoiD· 1 shared Florian NoackiD· 1 shared Kerstin Scholz· 1 shared Shushan ToneyaniD· 1 shared Simon AusländeriD· 1 shared Tony CijsouwiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Carlo De DonnoORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintAug 19, 2026

Assessing Codon Language Models for Context-Aware Codon Optimization in Nucleic Acid-Based Medicines

Shushan Toneyan, Kerstin Scholz, Carlo De Donno…·Joshua L. Payne

This study benchmarks three codon language models for optimizing nucleic acid-based medicines, finding that while no single model excels across all tasks, they offer advantages in capturing translational context beyond codon frequency.

DOI 10.64898/2026.08.11.744178

deep learningbenchmark study

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