Author

Guangyao Shan

Fudan UniversityORCID 0000-0002-2993-5817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Cheng ZhaniD· 1 shared Dejun Zeng· 1 shared Di Zuo· 1 shared Guangyu Yao· 1 shared Gujie WuiD· 1 shared Guoshu BiiD· 1 shared Hong FaniD· 1 shared Huan ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Cheng ZhanORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 31, 2026

A curated human lactylome and protein language model framework enable accurate prediction and reveal local determinants of lysine lactylation

Zhengda Li, Youcheng Huang, Guangyao Shan…·Guangyu Yao

The paper introduces CLEAR-Lactyl, a curated dataset of human lysine lactylation sites, and AttentionKla, a deep learning model that accurately predicts lactylation sites and reveals sequence determinants.

DOI 10.64898/2026.07.28.741267

humanproteomics

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Cancer BiologyeLifePeer-reviewedMay 9, 2024

Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

Yiwei Huang, Gujie Wu, Guoshu Bi…·Cheng Zhan

This study uses scRNA-seq to analyze how chemotherapy remodels the immune landscape and metabolic state in lung adenocarcinoma, identifying changes in macrophage subtypes and immune responses.

11 citations

humanscRNA-seq

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