Ghanendra Singh

The paper proposes a spatiotemporal cortical field model to simulate complex spiral traveling waves and their dynamics in local cortical circuits.

The paper proposes a model of senescent cell subtypes transition and identifies a molecular circuit involving NOTCH1 and C/EBPβ that mediates phenotypic switching between beneficial and deleterious senescent states.

The paper proposes a mathematical model of astrocytic sleep-awake homeostasis that explains the regulation of sleep pressure and synaptic strength dynamics through feedback control loops.

The paper proposes a simplified model to explain how senescent tumor cells are cleared by NK cells and how a two-punch therapy could regulate tumors through immune-tumor interactions.

The paper proposes a modular mathematical model to explain replication fork control dynamics in yeast, with potential applications to mammalian systems.

The paper develops a mathematical model to explain telomere length homeostasis in yeast, showing how feedback loops and delays lead to oscillations in telomere length.