Intravenous BCG immunization drives naive CD4+ T cell to Th1 differentiation via CD4+ T cell epigenetic reprogramming
Ruilin Wang, Yuanhui Zhao, Jie An Yang…·Erguang Li
This study shows that IV BCG immunization promotes Th1 differentiation of naive CD4+ T cells through epigenetic reprogramming and enhances antiviral activity against RSV.