Author

Mengyu Zhang

State Key Laboratory of Pharmaceutical BiotechnologyORCID 0000-0001-9375-6664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Bin ZhangiD· 1 shared Chenyu Xu· 1 shared Chuanjiang Yang· 1 shared Die Hu· 1 shared Erguang LiiD· 1 shared Fangfang Huang· 1 shared Jie An YangiD· 1 shared Jin-Zhang ZengiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Bin ZhangORCID

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2 papers

Recent·Most cited

Intravenous BCG immunization drives naive CD4+ T cell to Th1 differentiation via CD4+ T cell epigenetic reprogramming

Ruilin Wang, Yuanhui Zhao, Jie An Yang, Renjie Luo, Weikang Sun, Mengyu Zhang, Xiangdong Liu, Yayi Hou, Peng Cao, Erguang Li

This study shows that IV BCG immunization promotes Th1 differentiation of naive CD4+ T cells through epigenetic reprogramming and enhances antiviral activity against RSV.

bioRxiv · May 23, 2025 · PreprintImmunology

Homoharringtonine Promotes FTO Degradation to Suppress LILRB4-Mediated Immune Evasion in Acute Monocytic Leukemia

Fangfang Huang, Xiang Luo, Mengyu Zhang, Le Jin, Wenxin Sun, Peihan Chen, Xiuli Hong, Chenyu Xu, Meizhi Jiang, Die Hu, Bin Zhang, Shengwei Hu, Chuanjiang Yang, Rui Gao, Jin-Zhang Zeng, , Siming Chen

This study shows that homoharringtonine promotes FTO degradation, reducing LILRB4 expression and enhancing immune recognition in acute monocytic leukemia.

bioRxiv · Mar 15, 2025 · PreprintCancer Biology