Developmental BiologybioRxivPreprint
Regulatory mutants of the Tbx1 gene alter transcription programs of lineage determination and patterning in early mesoderm.
Sara Allegretti, Olga Lanzetta, Marchesa Bilio…·Antonio Baldini
This study identifies regulatory sequences of the Tbx1 gene and shows their deletion disrupts cardiopharyngeal lineage specification and embryonic patterning, leading to pharyngeal defects.
DOI 10.64898/2026.08.08.743664