Author

Kristina Brazhnik

Albert Einstein College of MedicineORCID 0000-0002-3077-1952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alexander Y. MasloviD· 2 shared Jan VijgiD· 2 shared Xiao DongiD· 2 shared Allan W. WolkoffiD· 1 shared Lei ZhangiD· 1 shared Milan M. KinkhabwalaiD· 1 shared Moonsook LeeiD· 1 shared Omar Alani· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Alexander Y. MaslovORCID

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2 papers

Recent·Most cited

Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver

Kristina Brazhnik, Shixiang Sun, Omar Alani, Milan M. Kinkhabwala, Allan W. Wolkoff, Alexander Y. Maslov, Xiao Dong, Jan Vijg

The paper shows that somatic mutation frequencies increase with age in human liver hepatocytes but are lower in liver stem cells and organoids.

Science Advances · Jan 31, 2020Peer-reviewedGenomics

Spontaneous retrotranspositions in normal tissues are rare and associated with cell-type-specific differentiation

Xiao Dong, Lei Zhang, Kristina Brazhnik, Moonsook Lee, Xiaoxiao Hao, Alexander Y. Maslov, Zhengdong Zhang, Tao Wang, Jan Vijg

The paper identifies rare spontaneous retrotranspositions in normal human tissues, showing cell-type-specific variation and association with differentiation processes.

bioRxiv · Jan 31, 2019 · PreprintGenomics