Author

Adrienne G. Randolph

Boston Children's HospitalORCID 0000-0002-3084-3071Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

Christoph LangeiD· 3 shared Georg HahniD· 3 shared Julian HeckeriD· 3 shared Sanghun LeeiD· 3 shared Scott T. WeissiD· 3 shared Dmitry ProkopenkoiD· 2 shared Lindsey Robert BadeniD· 2 shared Surender KhuranaiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBioinformatics

Christoph LangeORCID

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3 papers

Recent·Most cited

Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest

Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Jonathan Abraham, Tanya Novak, Julian Hecker, Michael Cho, Surender Khurana, Lindsey Robert Baden, Adrienne G. Randolph, Scott T. Weiss, Christoph Lange

BMC Bioinformatics · Dec 19, 2022Peer-reviewedBioinformatics

Unsupervised genome-wide cluster analysis: nucleotide sequences of the omicron variant of SARS-CoV-2 are similar to sequences from early 2020

Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Tanya Novak, Julian Hecker, Surender Khurana, Lindsey Robert Baden, Adrienne G. Randolph, Scott T. Weiss, Christoph Lange

The paper uses unsupervised cluster analysis to show that omicron variant SARS-CoV-2 sequences are most similar to early 2020 sequences, suggesting long-term circulation.

bioRxiv · Dec 29, 2021 · PreprintBioinformatics

Two mutations in the SARS-CoV-2 spike protein and RNA polymerase complex are associated with COVID-19 mortality risk

Georg Hahn, Chloe M. Wu, Sanghun Lee, Julian Hecker, Sharon Marie Lutz, Sebastien Haneuse, Dandi Qiao, Dawn Lisa DeMeo, Manish Chandra Choudhary, Behzad Etemad, Abbas Mohammadi, Elmira Esmaeilzadeh, Michael H. Cho, Rudolph E. Tanzi, Jonathan Z. Li, , Christoph Lange

The paper identifies two SARS-CoV-2 genome loci associated with increased COVID-19 mortality risk using logistic regression on whole-genome sequencing data.

bioRxiv · Nov 17, 2020 · PreprintGenomics