Author

Eusebio Navarro

Universidad de MurciaORCID 0000-0002-3091-4378Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:fungi (other)· 5 Research Focus:gene regulatory network inference· 5 Approach:statistical model· 5 Assay:DNA methylation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Francisco Esteban NicolásiD· 6 shared Victoriano GarreiD· 6 shared Carlos LaxiD· 5 shared Ghizlane TahiriiD· 5 shared Igor V. GrigorieviD· 2 shared Macario Osorio-ConcepcióniD· 2 shared Natalia Nicolás-MuñoziD· 2 shared Ulrike BinderiD· 2 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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6 shared papersGenetics

Francisco Esteban NicolásORCID

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6 papers

Recent·Most cited

Active histone modifications fine-tune DNA N-6 methyladenine deposition and maintain transcriptional stability

Carlos Lax, Macario Osorio-Concepción, Natalia Nicolás-Muñoz, Ghizlane Tahiri, Stephen James Mondo, Vivian Ng, Eusebio Navarro, Igor V. Grigoriev, Víctor Meza‐Carmen, Francisco Esteban Nicolás, Victoriano Garre

The paper characterizes the genome-wide interaction between active histone modifications and DNA 6mA in Rhizopus microsporus, showing they define chromatin domains and regulate transcriptional stability.

bioRxiv · Jul 21, 2026 · PreprintGenetics

Genome-wide Discovery of lncRNAs in Mucorales Reveals Essential Roles in Development and Fungal Biology

Ghizlane Tahiri, Hrant Hovhannisyan, Carlos Lax, Eusebio Navarro, Toni Gabaldón, Francisco Esteban Nicolás, Victoriano Garre

This study identifies and characterizes lncRNAs in Mucorales fungi, revealing their roles in development and pathogenicity, and highlights their potential as antifungal targets.

bioRxiv · Oct 1, 2025 · PreprintGenetics

A BRCT Domain-Containing Protein Induced in Early Phagocytosis Plays a Crucial Role in Mucorales Pathogenesis

Ghizlane Tahiri, Carlos Lax, Ulrike Binder, Jakob Scheler, Eusebio Navarro, Francisco Esteban Nicolás, Victoriano Garre

The paper identifies virulence genes in Mucorales fungi through transcriptomic analysis and functional validation, showing species-specific effects on virulence in different fungal species.

bioRxiv · May 13, 2025 · PreprintGenetics

Genome-wide exploration of the transcriptional regulatory landscape in the early-diverging fungus R. microsporus reveals pervasive DNA methyl adenine regulatory network

Carlos Lax, Leo A. Baumgart, Ghizlane Tahiri, Natalia Nicolás-Muñoz, Yu Zhang, Ian K. Blaby, Ronan C. O’Malley, Vivian Ng, Eusebio Navarro, Igor V. Grigoriev, Francisco Esteban Nicolás, Victoriano Garre

The paper uses DAP-seq to analyze TF binding sites in R. microsporus, revealing DNA methylation's role in gene regulation and expanding fungal motif catalogs.

bioRxiv · Jan 24, 2025 · PreprintGenetics

H3K4 methylation regulates development, DNA repair, and virulence in Mucorales

Macario Osorio-Concepción, Carlos Lax, Damaris Lorenzo-Gutiérrez, José Tomás Cánovas-Márquez, Ghizlane Tahiri, Eusebio Navarro, Ulrike Binder, Francisco Esteban Nicolás, Victoriano Garre

This paper investigates the role of H3K4 methylation in Mucorales fungi, showing it regulates development, DNA repair, and virulence through genetic and phenotypic analyses of set1 knockout strains.

IMA Fungus · Mar 14, 2024Peer-reviewedGenetics

A non-canonical RNAi pathway controls virulence and genome stability in Mucorales

Carlos Pérez Arques, María Isabel Navarro-Mendoza, Laura Murcia, Eusebio Navarro, Victoriano Garre, Francisco Esteban Nicolás

This paper identifies a non-canonical RNAi pathway (NCRIP) in Mucor circinelloides that regulates virulence and genome stability by controlling transposon activity and stress responses.

PLoS Genetics · Jul 13, 2020Peer-reviewedGenetics