Jaesuk Yun

DTCAMD, a disease-associated truncated form of CRYAB in neovascular age-related macular degeneration: a potential driver of subretinal fibrosis

This study identifies a truncated form of CRYAB, DTCAMD, as a potential therapeutic target for subretinal fibrosis in nAMD.

Acute head shaking precedes chronic corpus callosum deficits during repeated cocaine exposure in common marmosets

This study shows that acute cocaine-induced head shaking precedes chronic corpus callosum deficits and identifies DPYSL2 and CRYAB as potential molecular markers of cocaine-induced white matter changes.

Integrated pharmacological and structural profiling reveals CB1 residue interaction patterns associated with synthetic cannabinoid receptor agonist efficacy

The paper analyzes the pharmacological and structural features of synthetic cannabinoid receptor agonists to identify receptor interaction patterns linked to their efficacy.

Restoration of circulating 2-arachidonoylglycerol levels attenuates cocaine self-administration through endocannabinoid-dopamine interactions in common marmosets

This study shows that restoring 2-AG levels reduces cocaine self-administration in marmosets by modulating dopamine and GPR55/DAT interactions.