Author

Alexander R Hummels

University of PittsburghORCID 0000-0002-3114-8871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Carlos Jaime CamachoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

Systems BiologybioRxivPreprintSep 29, 2025

Cell-type-agnostic differential gene expression uncovers conserved principles of cellular regulation

Alexander R Hummels, Carlos Jaime Camacho

The paper introduces consensus signatures to identify conserved gene regulation principles across cell types and finds ORC1 down-regulation by CDK4/6 inhibitors disrupts a feedback loop for E2F2-driven proliferation.

DOI 10.1101/2025.09.29.679285

humanbulk RNA-seq

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