Increased excitation-inhibition ratio stabilizes synapse and circuit excitability in four autism mouse models.
Michelle W. Antoine, Tomer Langberg, Philipp Schnepel, Daniel E. Feldman
The paper tests the hypothesis that autism mouse models have increased excitation-inhibition ratio in cerebral cortex, finding it reflects homeostatic stabilization rather than hyperexcitability.
Neuron · Jan 21, 2019Peer-reviewedNeuroscience