Daniel E. Feldman

The paper investigates experience-dependent plasticity in somatostatin interneurons and identifies two-pore potassium (K2P) channels as a mechanism underlying this plasticity.

The paper shows that Scn2a loss-of-function in mice causes degraded sensory coding in the cortex, which is rescued by CRISPRa gene activation.

The paper uses optogenetics to determine the laminar origins of high-gamma and low-frequency ECoG signals in mice, finding that L5 suppression affects high frequencies while L2/3 suppression affects low frequencies.

The paper shows that mice shift attention between whiskers based on recent reward history, with specific neural correlates in the somatosensory cortex.

The paper constructs a single-nucleus transcriptomic atlas of the mouse whisker somatosensory cortex during development and finds that sensory experience minimally affects cell type maturation in this region, unlike the visual cortex.

The paper shows that PV circuit homeostasis is impaired in two autism models, Tsc2+/- and Fmr1-/-, at both physiological and molecular levels.

This study examines tactile coding in Cntnap2-/- mice, finding no excess spiking but degraded and unstable somatotopic coding in the somatosensory cortex.

The paper improves positively tuned voltage indicators by enhancing their kinetics and contrast for better spike detection.

The paper identifies that VIP interneurons in mouse whisker S1 are activated by both whisker stimuli and goal-directed licking during a Go/NoGo task.

This paper introduces a template matching method for spike detection in extracellular recordings, showing improved detection of spikes during high firing rates and noisy conditions.

This study shows that tactile enrichment in mice enhances functional columnar organization and improves sensory coding in layer 2/3 of the somatosensory cortex.

This study investigates whisker map organization in awake mice during different behavioral tasks, finding that task demands alter the fine-scale structure and correlation patterns of whisker tuning in cortical neurons.

The paper tests the hypothesis that autism mouse models have increased excitation-inhibition ratio in cerebral cortex, finding it reflects homeostatic stabilization rather than hyperexcitability.