Central opioid receptors mediate morphine-induced itch and chronic itch
Zilong Wang, Changyu Jiang, Hongyu Yao, Chen Ouyang, Sreya Rahman, Yun Gu, Junli Zhao, Yul Huh, Ru‐Rong Ji
This study shows that morphine-induced itch is mediated by central opioid receptors on spinal inhibitory interneurons, and chronic itch can be treated with CNS-targeted naloxone.
Brain · Nov 19, 2020Peer-reviewedNeuroscience