Changyu Jiang

This study identifies GPR37L1 in satellite glial cells as a regulator of pain control through interactions with potassium channels and maresin 1, showing its role in neuropathic pain resolution.

This study shows that male mice benefit from intrathecal BMSCs and TGF-β1 for CIPN relief, while female mice do not, highlighting sex differences in pain modulation.

This study shows PD-1 in hippocampal neurons regulates excitability, synaptic plasticity, and cognition, with anti-PD-1 improving cognitive function in mice and primates.

The paper develops a PAR3 agonist and shows it induces mechanical hypersensitivity in mice, suggesting PAR3's role in nociception and plasticity.

This study shows that morphine-induced itch is mediated by central opioid receptors on spinal inhibitory interneurons, and chronic itch can be treated with CNS-targeted naloxone.

The paper identifies kenpaullone as a compound that enhances KCC2 expression and reduces pathologic pain by restoring inhibitory neurotransmission in mouse models.

This study shows that PD-1 is required for morphine analgesia and MOR signaling in neurons, with PD-L1 enhancing morphine's pain-relieving effects.