BiophysicsbioRxivPreprint
Zero-Shot Generation of Protein Conformational Ensembles Through AlphaFold Latent Flooding
Runtong Qian, Rui Zhan, Zilin Song, Jing Huang
This paper introduces AFLF, a method to generate diverse protein conformations from sequence using AlphaFold's latent space, showing it captures structural fluctuations and binding sites.
DOI 10.64898/2026.04.16.718914