Author

Runtong Qian

Westlake UniversityORCID 0009-0005-8743-4833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Jing HuangiD· 2 shared Rui ZhaniD· 2 shared Qi HuiD· 1 shared Wenyi ZhangiD· 1 shared Yuxing WangiD· 1 shared Zilin SongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

Jing HuangORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 27, 2026

Zero-Shot Generation of Protein Conformational Ensembles Through AlphaFold Latent Flooding

Runtong Qian, Rui Zhan, Zilin Song, Jing Huang

This paper introduces AFLF, a method to generate diverse protein conformations from sequence using AlphaFold's latent space, showing it captures structural fluctuations and binding sites.

DOI 10.64898/2026.04.16.718914

protein structuredeep learning

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedFeb 16, 2026

Deciphering DEL Pocket Patterns Through Contrastive Learning

Wenyi Zhang, Yuxing Wang, Rui Zhan…·Jing Huang

This paper introduces ErePOC, a contrastive learning model for representing protein binding pockets, which improves DEL target selection by identifying shared characteristics and functional similarities.

2 citationstop 4%

humanprotein structure

𝕏 PostBluesky