Integrated small and long RNA sequencing in single oocytes reveals piRNA-mediated transposon repression during human oogenesis
Fengjuan Zhang, Hongdao Zhang, Yali Xiao, Miao Liu, Aimin Ren, Suying Liu, Ligang Wu
The paper profiles small and long RNA in human oocytes across stages, showing short-piRNAs broadly suppress transposons while long-piRNAs target specific ERVs.
bioRxiv · Jul 22, 2025 · PreprintGenomics