A microbiome meta-transcriptomics pipeline identifies a novel human neutrophil elastase inhibitor that protects the colonic epithelial barrier
Bojan Stojkovic, Matthijs Bekkers, Jake P. Violi, Brett Anthony Neilan, Simon Keely, William A. Donald, Carlos Riveros, Gerard E. Kaiko
The paper identifies a novel microbiota-derived protein, BMG-1, that inhibits neutrophil elastase and protects the intestinal barrier in IBD.
bioRxiv · Sep 11, 2025 · PreprintMicrobiology