On the automatic annotation of gene functions using observational data and phylogenetic trees
George G. Vega Yon, Duncan C. Thomas, John L. Morrison, Huaiyu Mi, Paul D. Thomas, Paul Marjoram
This paper develops a probabilistic model using phylogenetic trees and Gene Ontology annotations to predict gene functions, showing scalability and agreement with biological intuition.
PLoS Computational Biology · Feb 18, 2021Peer-reviewedBioinformatics