Paul Marjoram

The paper introduces MANGO, a network-based method to detect gene set clustering by conditioning on network topology and gene degree, showing improved performance over existing approaches.

The paper shows that epigenetic conservation of genes correlates with their functional importance in human cells and drug sensitivity.

This paper develops a probabilistic model using phylogenetic trees and Gene Ontology annotations to predict gene functions, showing scalability and agreement with biological intuition.

The paper estimates the effective population size and somatic mutation rate in asexual planarians using population genetic models and pedigree data.

HiLDA identifies mutational patterns and their frequencies in cancer data, showing significant associations with mutation timing in colon cancer.