The Kaposi's sarcoma-associated herpesvirus viral genome packaging accessory factor ORF68 forms cytoplasmic puncta dependent on the viral tyrosine kinase
Sara Gelles-Watnick, Dawei Liu, Mayte A Cerezo-Matias, Jessica Liu, Giancarlo Ospina, Alicia Schäfer, Lilian Kabeche, Ileana M. Cristea, Allison L. Didychuk
This study identifies a novel cytoplasmic function of the KSHV packaging factor ORF68, dependent on its interaction with the viral tyrosine kinase ORF21.
bioRxiv · Feb 23, 2026 · PreprintMicrobiology