Author

Brian D. Poole

Brigham Young UniversityORCID 0000-0002-3205-640XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Bradford K. BergesiD· 1 shared Brett E PickettiD· 1 shared Joshua S. Ramsey· 1 shared Macey C. Call· 1 shared Sidney T. SitholeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

Bradford K. BergesORCID

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1 paper

Recent·Most cited

Host gene expression changes induced by an HIV-1 mutant associated with delayed AIDS progression reveal potential mechanisms

Sidney T. Sithole, Joshua S. Ramsey, Macey C. Call, Brian D. Poole, Brett E Pickett, Bradford K. Berges

The paper identifies 289 differentially expressed genes in HIV-1 R77Q-infected cells compared to wild-type, revealing an apoptotic signature and failure to upregulate anti-apoptotic genes like bcl-2.

bioRxiv · Feb 18, 2026 · PreprintMicrobiology