Yan Xu

This paper introduces PocketXMol, a generative foundation model for molecular interactions with protein pockets, achieving state-of-the-art performance in 11 tasks and demonstrating success in designing inhibitors and peptides.

This study identifies DPEP1 as a prognostic marker in adult B-cell acute lymphoblastic leukemia, showing its role in proliferation and survival through phosphCREB and p53 regulation.