Author

Paul A. Watkins

Kennedy Krieger InstituteORCID 0000-0002-3246-1405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Elizabeth Anne Kolar· 2 shared Emily M. Clay· 2 shared Xiaohai ShiiD· 2 shared Ann B. MoseriD· 1 shared Bachchu LaliD· 1 shared Domingo González‐LamuñoiD· 1 shared John E. Locke· 1 shared Kirby D. SmithiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Elizabeth Anne Kolar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Toward pharmacologic therapy for glioblastoma: Characterization of the very long-chain acyl-CoA synthetase 3 (ACSVL3) inhibitor Grassofermata

Emily M. Clay, Xiaohai Shi, Elizabeth Anne Kolar, Yanqiu Liu, Bachchu Lal, Paul A. Watkins

This study identifies CB5 (grassofermata) as a potential inhibitor of ACSVL3, showing reduced glioma cell growth and malignancy in vitro and in vivo.

bioRxiv · Jul 8, 2026 · PreprintCancer Biology

Toward pharmacologic therapy for glioblastoma: Identifying inhibitors of very long-chain acyl-CoA synthetase 3 (ACSVL3)

Emily M. Clay, Xiaohai Shi, Elizabeth Anne Kolar, Mayur D. Mody, John E. Locke, Paul A. Watkins

This paper identifies potential inhibitors of ACSVL3, an enzyme overexpressed in glioblastoma, using in vitro assays and a high-throughput screening approach.

bioRxiv · Jul 2, 2025 · PreprintBiochemistry

Role of ACSBG1 in brain lipid metabolism and X-linked adrenoleukodystrophy pathogenesis: Insights from a knockout mouse model

Xiaoli Ye, Yuanyuan Li, Domingo González‐Lamuño, Zhengtong Pei, Ann B. Moser, Kirby D. Smith, Paul A. Watkins

This study investigates ACSBG1's role in brain lipid metabolism and XALD using a knockout mouse model, revealing altered fatty acid profiles but no direct link to XALD pathology.

Cells · Oct 12, 2024Peer-reviewedBiochemistry