This study identifies two distinct pancreatic cancer subtypes through proteogenomic analysis and links them to altered molecular pathways and clinical outcomes.

PLoS ONE · Sep 10, 2021Peer-reviewedBioinformatics

ELF4 Expression is Associated with Worse Disease Outcomes and Increased Resistance to Anticancer Agents in Human Cancers

Doris Kafita, Victor Daka, Panji Nkhoma, Mildred Zulu, Ephraim Zulu, Rabecca Tembo, Zifa Ngwira, Florence Mwaba, Musalula Sinkala, Sody Mweetwa Munsaka

The paper investigates ELF4 expression in human cancers, finding it correlates with worse outcomes and drug resistance across 32 cancer types.

PLoS ONE · Apr 9, 2021Peer-reviewedGenetic & Genomic Medicine

A Systems Approach Identifies Key Regulators of HPV-Positive Cervical Cancer

Musalula Sinkala, Mildred Zulu, Panji Nkhoma, Doris Kafita, Ephraim Zulu, Rabecca Tembo, Zifa Ngwira, Victor Daka, Sody Mweetwa Munsaka

This study identifies key regulatory pathways and proteins in HPV-positive cervical cancer through systems-level analysis, suggesting potential drug targets.

Journal of Bioinformatics and Systems Biology · Jan 1, 2021Peer-reviewedGenetic & Genomic Medicine