Jason C. Hyun

Interpreting roles of mutations associated with the emergence of S. aureus USA300 strains using transcriptional regulatory network reconstruction

The paper identifies mutations in S. aureus USA300 strains that affect gene regulation by combining genetic association testing with transcriptional regulatory network reconstruction.

The Pangenome of Escherichia coli

The paper analyzes the pangenome of Escherichia coli using 2,377 genomes to define accessory genes and rare genomic variation across phylogroups.

Pangenome analysis reveals the genetic basis for taxonomic classification of the Lactobacillaceae family

This study performs a pangenome analysis of the Lactobacillaceae family, revealing correlations between pangenome openness, transposon abundance, and species-specific genomic features.

Global pathogenomic analysis identifies known and novel genetic antimicrobial resistance determinants in twelve species

The paper identifies known and novel antimicrobial resistance genes across 12 species using pangenomics, gene annotation, and machine learning, finding gene transfer is mostly species-specific and demonstrating improved methods for AMR gene discovery.