Organoid Modeling and Single-Cell Profiling Uncover the Migration Mechanism of Smooth Muscle Cells in Moyamoya Disease
Shihao He, Junze Zhang, Xilong Wang, Zhen Qi, Zhenyu Zhou, Yanru Wang, Shaoqi Xu, Dandan Li, Xun Ye, Ziqi Liu, Xiaokuan Hao, Yuanli Zhao, Rong Wang
This study uses organoid models and single-cell profiling to identify TUBA4A and TUBB4B overexpression as drivers of vascular smooth muscle cell dysfunction in Moyamoya Disease.
Communications Biology · Jan 7, 2026Peer-reviewedCell Biology