Author

Fengxian Li

Washington University in St. LouisORCID 0000-0002-3307-1468Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ajay K. DhakaiD· 1 shared Chang-Shen Qiu· 1 shared Chen Yao· 1 shared Ding Huijuan· 1 shared Gao Zhaobing· 1 shared Guodun ZhaoiD· 1 shared Hongfei ZhangiD· 1 shared Jing FengiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Ajay K. DhakaORCID

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2 papers

Recent·Most cited

A microbial-sensory axis drives Pseudomonas aeruginosa-induced mechanical itch

Pang Zhaohua, Ding Huijuan, Liu Huan, Q Wang, Wang Yu, Qianwen Zhu, Chen Yao, Guodun Zhao, Ximin Hu, Zhenru Chen, Zhou liqin, wang ting, Lefu Lan, Gao Zhaobing, Hongfei Zhang, , Fengxian Li

This study identifies bacterial flagellin as the driver of mechanical itch in Pseudomonas aeruginosa infections via TLR5 activation in specific sensory neurons.

bioRxiv · Jun 10, 2026 · PreprintNeuroscience

TRESK K+ Channel Activity Regulates Trigeminal Nociception and Headache

Zhaohua Guo, Chang-Shen Qiu, Xinhua Jiang, Jintao Zhang, Fengxian Li, Qin Liu, Ajay K. Dhaka, Yuqing Q. Cao

This study shows that TRESK K+ channel activity is required for trigeminal pain regulation, with loss of TRESK increasing headache-like behaviors in mice.

eNeuro · Jul 1, 2019Peer-reviewedNeuroscience