Author

Alasdair M. Mackenzie

Rutherford Appleton LaboratoryORCID 0000-0002-3308-6352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam S. NelsoniD· 1 shared Ajay JhaiD· 1 shared Andrew G. LeachiD· 1 shared Benjamin G. DavisiD· 1 shared Chris ArteriD· 1 shared Georgina L. Bonney· 1 shared Graham John HutchingsiD· 1 shared Maria LopatniukiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adam S. NelsonORCID

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1 paper

Recent·Most cited

High-throughput discovery of a dearomative cycloaddition enables dual photochemical-photophysical perturbative probing of protein function

Samuel D. Griggs, Yibo Zeng, Stefan Lohmann, Chris Arter, Samuel Liver, Yana Demyanenko, Sivaramakrishnan Ramadurai, Georgina L. Bonney, Maria Lopatniuk, Alasdair M. Mackenzie, Stanley W. Botchway, Andrew G. Leach, Graham John Hutchings, Shabaz Mohammed, Stephen P. Marsden, , Benjamin G. Davis

This paper develops a high-throughput method to discover a novel photochemical reaction for editing protein side chains and using it to probe protein function through combined photochemical and photophysical approaches.

bioRxiv · Oct 23, 2025 · PreprintBiochemistry