Mathieu Roy

A comprehensive physiological dataset of pain and aversive modalities for pain biomarkers research

This paper presents a comprehensive dataset of physiological and behavioural responses to pain and aversive stimuli for biomarker research.

Maintaining performance under pain is effortful: experimental and computational evidence

The paper shows that performance under pain is maintained through increased effort, supported by computational modeling, across cognitive and motor tasks.

Increased perceived effort during contralateral thermal heat pain is not explained by increased intracortical and corticospinal inhibition.

This study investigates whether contralateral thermal heat pain affects corticospinal and intracortical excitability, finding no reduction and instead increased corticospinal excitability, with perceived effort linked to pain experience rather than neural inhibition.

Facing pain is effortful: key role of the supplementary motor area and anterior midcingulate cortex

This study uses fMRI to investigate how brain regions like the supplementary motor area and anterior midcingulate cortex contribute to effort perception during pain and task performance.

Pain reflects the informational value of nociceptive inputs.

This study investigates how pain perception relates to prediction errors and learning, showing that unexpected pain increases subjective pain and physiological responses.

Modulating Subjective Pain Perception with Decoded MNI-space Neurofeedback

This study uses real-time fMRI decoding to modulate pain-related brain patterns and shows that participants can down-regulate pain signatures, correlating with changes in perceived pain intensity.

Different brain systems support the aversive and appetitive sides of human pain-avoidance learning

The paper investigates whether aversive and appetitive pain-avoidance learning use shared or separate systems, finding distinct neural pathways and dopaminergic/opioid regulation.

Effect sizes and test-retest reliability of the fMRI-based Neurologic Pain Signature

The paper evaluates the effect size and test-retest reliability of the Neurologic Pain Signature (NPS) across multiple studies, finding large within-person effect sizes and reliable performance with sufficient trial numbers.

The aversive value of pain in human decision-making

This study examines how the aversive value of pain influences human decision-making in the context of monetary rewards and electric shocks.

Evoked pain intensity representation is distributed across brain systems: A multistudy mega-analysis

This study investigates the spatial scale of acute pain representation using fMRI data from 289 participants, finding that distributed, multi-system models better capture pain intensity than single regions or networks.

Multiple brain networks mediating stimulus-pain relationships in humans

The paper identifies brain networks mediating stimulus-pain relationships using high-dimensional mediation analysis in fMRI data from 284 humans.