New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene
Amin Mirzaiebadizi, Mohammad Reza Ahmadian
This study characterizes the RAC1P29S mutation in melanoma, showing it hyperactivates signaling pathways by impairing GTP hydrolysis and altering effector interactions.
Cancer Gene Therapy · Oct 1, 2025Peer-reviewedCancer Biology