Author

Walter K. Schmidt

University of GeorgiaORCID 0000-0002-3359-3434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anushka SarkariD· 2 shared Emily R. HildebrandtiD· 2 shared June H Kim· 2 shared Emily T. Mai· 1 shared Khushi V. Patel· 1 shared La Ryel A Waldon· 1 shared Natarajan KannaniD· 1 shared Sumil S. Shah· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Anushka SarkarORCID

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2 papers

Recent·Most cited

Comprehensive analysis of CXXX sequence space reveals that S. cerevisiae GGTase-I mainly relies on a2X substrate determinants

Anushka Sarkar, Emily R. Hildebrandt, Khushi V. Patel, Emily T. Mai, Sumil S. Shah, June H Kim, Walter K. Schmidt

The paper evaluates S. cerevisiae GGTase-I specificity across all CXXX sequences, finding that non-canonical motifs with non-polar a2 and hydrophobic terminal residues are preferred.

bioRxiv · Mar 4, 2024 · PreprintGenetics

A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences

June H Kim, Emily R. Hildebrandt, Anushka Sarkar, Wayland Yeung, La Ryel A Waldon, Natarajan Kannan, Walter K. Schmidt

The paper evaluates all possible CXXX sequences as farnesyltransferase targets in yeast using a reporter system, revealing expanded specificity beyond the canonical CaaX motif.

G3 Genes Genomes Genetics · Apr 29, 2023Peer-reviewedGenetics