Christiane J. Ferran

Characterization of focused ultrasound blood-brain barrier disruption effect on inflammation as a function of treatment parameters

This study examines how FUS intensity and microbubble dose affect BBB disruption, microhemorrhage, and inflammation in mice brains, and evaluates sex differences and repeated treatment effects.

Integrated single-nuclei and spatial transcriptomic analysis reveals propagation of early acute vein harvest and distension injury signaling pathways following arterial implantation

The paper uses single-nuclei and spatial transcriptomics to analyze vein graft injury pathways, identifying key signaling networks involved in graft failure after harvest and implantation.