Author

Nick Todd

Brigham and Women's HospitalORCID 0000-0003-2588-6330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:imaging· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Paige Nowlin· 2 shared Yongzhi ZhangiD· 2 shared Akira SumiyoshiiD· 1 shared Alejandro Rivera-Olvera· 1 shared Andreas HeßiD· 1 shared Baogui B. Zhang· 1 shared Bridget FunkiD· 1 shared Carles JusticiaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Paige Nowlin

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 1, 2026

Technical Note: Focused ultrasound-mediated blood-brain barrier opening for delivery of LNP-packaged modRNA therapy in a mouse model of Niemann-Pick Disease Type C

Nick Todd, Bridget Funk, Paige Nowlin…·Olaf A. Bodamer

This study evaluates FUS-BBBO for delivering LNP-packaged modRNA to the cerebellum in NPC mice, finding BBB opening but no detectable protein expression or therapeutic benefit.

DOI 10.64898/2026.06.30.735564

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceBiomedicine & PharmacotherapyPeer-reviewedDec 23, 2024

Characterization of focused ultrasound blood-brain barrier disruption effect on inflammation as a function of treatment parameters

Cleide Angolano, Emily Hansen, Hala Ajjawi…·Nick Todd

This study examines how FUS intensity and microbubble dose affect BBB disruption, microhemorrhage, and inflammation in mice brains, and evaluates sex differences and repeated treatment effects.

29 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintSep 27, 2024

Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline.

Marie E Galteau, Margaret Broadwater, Yi Chen…·Joanes Grandjean

The paper assesses consistency of rat fMRI results across 12 centers using a unified pipeline and identifies variability due to experimental differences.

1 citation

ratimaging

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