Tristan Wagner

Molecular basis of N2 fixation in a hyperthermophilic archaeon

This study investigates the N2-fixing system of Methanocaldococcus infernus, revealing structural insights into its thermostable nitrogenase and unifying mechanistic principles across nitrogenase types.

Molecular mechanism of nitrogenase sequestration by a PII-protein couple

This paper elucidates how anaerobes regulate nitrogenase activity through the PII-protein couple NifI1 and NifI2, revealing a structural mechanism for energy-dependent N2-fixation control.

Carbon monoxide-driven bioethanol production operates via a tungsten-dependent catalyst

The paper demonstrates that carbon monoxide-driven ethanol production in Clostridium autoethanogenum uses a tungsten-dependent aldehyde:ferredoxin oxidoreductase, with ferredoxin facilitating electron transfer and enzyme activity.

Atomic resolution structures of the methane-activating enzyme in anaerobic methanotrophy reveal extensive post-translational modifications.

The paper determines atomic structures of MCRs from anaerobic methanotrophic archaea, revealing conserved structures and post-translational modifications.

Mini-bacterioferritins: Structural insight into a new type of ferritin-like protein from an anaerobic methane-oxidising archaeon

The paper identifies and characterizes mini-bacterioferritin, a novel ferritin-like protein from an anaerobic methane-oxidizing archaeon, revealing its structure and evolutionary relationships.

Snapshots of acetyl-CoA synthesis, the final step of CO2 fixation in the Wood-Ljungdahl pathway

The paper presents structural snapshots of the CODH/ACS complex in CO2 fixation, revealing conformational changes and reaction mechanisms for acetyl-CoA synthesis.