The chromatin remodeler LSH controls genome-wide cytosine hydroxymethylation
Maud de Dieuleveult, Martin Bizet, Laurence Colin, Emilie Calonne, Martin Bachman, Chao Li, Irina Stancheva, Benoît Miotto, François Fuks, Rachel Deplus
This study shows that LSH regulates 5-hydroxymethylcytosine levels in mouse cells, with TET proteins relying on LSH to establish genome-wide 5hmC patterns.
Epigenetics · May 7, 2021Peer-reviewedMolecular Biology