Author

Graeme John Sills

University of GlasgowORCID 0000-0002-3389-8713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Anthony Guy MarsoniD· 2 shared Bobby P.C. KoelemaniD· 2 shared Chantal DepondtiD· 2 shared Federico ZaraiD· 2 shared Gianpiero L. CavalleriiD· 2 shared Holger LercheiD· 2 shared John J. CraigiD· 2 shared Josemir W. A. S. SanderiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Anthony Guy MarsonORCID

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Author profile →

2 papers

Recent·Most cited

Transcription factor binding and individual genetic risk for valproate teratogenicity

Alison Anderson, Piero Perucca, Elena Vianca, Daniel Sandvik, Ana Antonic‐Baker, Roland Krause, Dana Jazayeri, Alison Anne Hitchcock, Janet Elizabeth Graham, Marian Todaro, Torbjörn Tomson, Dina Battino, Emilio Perucca, Meritxell Martínez Ferri, Anne Maria Rochtus, , Sameer M. Zuberi

The paper investigates how genetic variants affecting transcription factor binding contribute to valproate-induced birth defects and identifies EP300 as a key regulator involved in this process.

Neurology · Jan 14, 2026Peer-reviewedGenetic & Genomic Medicine

Predicting Drug Response with Multi-Task Gradient-Boosted Trees in Epilepsy

Julia Hellmig, Christian M. Boßelmann, Roland Krause, Patrick May, Stefan Wolking, Gianpiero L. Cavalleri, Norman Delanty, John J. Craig, Chantal Depondt, Bobby P.C. Koeleman, Anthony Guy Marson, Terence John O'Brien, Josemir W. A. S. Sander, Graeme John Sills, Pasquale Striano, , Nico Pfeifer

This paper predicts drug response in epilepsy using multi-task gradient-boosted trees, identifying key genomic and clinical features that influence treatment outcomes.

bioRxiv · Aug 12, 2025 · PreprintBioinformatics