Cancer BiologyScience AdvancesPeer-reviewed
TCF3::HLF Orchestrates an Enhancer-Promoter Network with Activation of MEF2C to Promote Immature HSC gene Expression in Leukemia
Valdemar Priebe, Bartimée Galvan, Aneta Drakul…·Jean‐Pierre Bourquin
This study identifies TCF3::HLF's role in rewiring the 3D genome to drive leukemia by regulating MEF2C and altering hematopoietic stem cell gene expression.