Katherine J. Wozniak

DNA replication initiation timing is important for maintaining genome integrity

This study investigates how DNA replication initiation frequency affects genome stability in Bacillus subtilis, showing that both under-initiation and over-initiation lead to DNA damage sensitivity and replication fork stress.

RNase H genes cause distinct impacts on RNA:DNA hybrid formation and mutagenesis genome-wide

This study examines the distinct roles of RNase HII and HIII in removing RNA:DNA hybrids and their impact on mutagenesis and DNA replication.