Jue D. Wang

The paper shows that pGpp production in Bacillus subtilis causes faster translation inhibition than ppGpp or pppGpp through GTP depletion and transcriptome remodeling.

The paper identifies pyruvate kinase's role in GTP synthesis during glycolysis in bacteria, showing it reduces guanosine toxicity and contributes to NTP production.

This study identifies allosteric regulation of pyruvate kinase in Bacillus subtilis as critical for efficient gluconeogenesis by preventing metabolic conflicts and carbon overflow.

The paper introduces a new image analysis pipeline for mother machine data and evaluates its performance against existing tools, highlighting parameter sensitivity and segmentation biases.

This study examines the distinct roles of RNase HII and HIII in removing RNA:DNA hybrids and their impact on mutagenesis and DNA replication.

MM3 is a modular image analysis pipeline for mother machine experiments that converts raw images into cell feature data within a day.