Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC
Antony K. Sorial, Ines M.J. Hofer, Maria Tselepi, Kathleen Cheung, Eleanor L. Parker, David John Deehan, Sarah J. Rice, John A. Loughlin
This study investigates the functional effects of the OA-associated SNP rs11780978 on PLEC methylation and expression across multiple tissues, revealing tissue-specific impacts.
Osteoarthritis and Cartilage · Jun 21, 2020Peer-reviewedGenetics