Author

Thomas M. Drake

Cancer Research UK Scotland InstituteORCID 0000-0002-3425-0177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan James StewartiD· 1 shared Alejandro Huerta UribeiD· 1 shared Allan J. B. WatsoniD· 1 shared David P. SumptoniD· 1 shared David S. MouraiD· 1 shared Guillaume PiesseniD· 1 shared Hasnain Ahmed· 1 shared Keira Hughes· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alan James StewartORCID

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1 paper

Recent·Most cited

L-pentahomoserine correlates with therapy outcome in esophageal cancer and promotes metabolic adaptations that support cell survival under nutrient-deprived conditions

Mark E. Kelly, Alejandro Huerta Uribe, Micheale Cerna, Keira Hughes, Hasnain Ahmed, Marco Fernandes, Kevin M. Rattigan, Ruhi S. Deshmukh, David S. Moura, Swati Arya, Stephanie May, Miryam Müller, Thomas M. Drake, Αναστασία Γεωργακοπούλου, Thomas Graham Bird, , Victor Hugo Villar

The paper identifies L-pentahomoserine as a bacterial metabolite linked to better survival in esophageal cancer by supporting metabolic adaptations under nutrient stress.

bioRxiv · Jan 15, 2026 · PreprintCancer Biology